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Benchtop Bioreactor
CBR100 series Benchtop bioreactor is one of the lightest and most compact of all similar bioreactors available in the market. The control tower has at least four built-in peristaltic pumps which are configurable for automated fluid addition.
CBR100 Series
Features
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Available culture vessels from 1L, 2L, 3L, 5L, 7L, 10L and 15L, up to 75% working volume.
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4 built-in peristaltic pumps
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Autoclave sterilization
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Boro3.3 glass vessel with top mechanical stirring, SS316L cover
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Sensors: PT100, DO, foam, pH
01
CULTURE VESSEL
· Material: Boro3.3 glass and SS316L (polishing better than Ra 0.4 um)
· Ratio: Diameter to height, about 1:2
· Rated Pressure:0.15 Mpa
· Working Pressure: ＜0.1Mpa
· Ports: 1 x fire ring, 1 x pH, 1 x DO, 1 x PT100, 1 x foam sensor, 1 x exhaust with condenser, spares
· Sterilization: Off-site sterilization (autoclavable)
· Sparge: SS316L ring sparger in the bottom
03
Datas
· Historical data export and curves;
· Fermentation/culture batch record;
· Calibration of sensors and peristaltic pumps;
· 3-level authority setting & control;
· Record historical operations
02
PH
· pH control coupled with peristaltic pump or CO2;
· Manual pH control by peristaltic pump;
Temperature
· Robust PID algorithm;
· Electrical-heating by SS316L electric hot plate at vessel bottom, chilled by tap or chilled water supply;
· Sequential control coupled with fermentation process;
Agitation
· Robust PID algorithm;
· Manual speed control or speed control coupled with other parameters;
· Agitation speed control coupled with other parameters (like DO);
Foam
· Foam control coupled with peristaltic pump; (anti-foam);
· Mechanical defoaming blade;
DO
· Cascade control, coupled with different parameters (agitation, gas inlet and peristaltic pump);
CBR100 PROJECTS
Gassing Strategies
Application-appropriate spargers are available for microbiology and cell culture. The system selects corresponding gassing strategies for different sizes and types of fermenters. And the gas flow rate can be adjusted manually by a precision rotameter or automatically by an optional MFC.
CELL CULTURE
Additive Flow
Simultaneous gassing strategy of overlay and sparger: air goes into overlay through a flow meter and a solenoid valve. Solenoid valves select air, O2, N2 and CO2 to flow to the sparger. An additional airflow path can be added to the distributor. Mass flowmeter is optional for each gas inlet.
MICROBIAL RESEARCH
O₂-Enrichment
Utilizing two flow paths for air and O2 flow, the flow meter intuitively indicates and allows manual adjustment of the sparger flow rate. O2 is pulsed through a solenoid valve and flows only as needed to maintain the Dissolved Oxygen (DO) set point. No air is provided at this time. A mass flow controller can be integrated to measure and control the total gas flow range by manual adjustment or automatically combined with a DO controller.
Select Your Bioreactors
Model | Total Volume | Application |
|---|---|---|
CBR100-C1-1L | 1L | Cell Culture |
CBR100-C1-2L | 2L | Cell Culture |
CBR100-C1-3L | 3L | Cell Culture |
CBR100-C1-4L | 4L | Cell Culture |
CBR100-C1-5L | 5L | Cell Culture |
CBR100-C1-7L | 7L | Cell Culture |
CBR100-C1-10L | 10L | Cell Culture |
CBR100-C1-15L | 15L | Cell Culture |
